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Anti-TNIP3PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-TNIP3 Polyclonal Antibody品牌：solarbio | 貨號：K007570P

英文名稱Anti-TNIP3 Polyclonal Antibody
宿主Rabbit
別名LIND;ABIN-3
應用WB
稀釋比例WB 1:200-1000.
交叉反應 Human Mouse
蛋白分子量39kDa
Gene ID79931
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human TNIP3
性狀液體
Public Immunogen RangeA synthetic peptide of human TNIP3
Swiss ProtQ96KP6
克隆類型 Polyclonal Antibody
背景資料TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

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