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Anti-CD8BPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CD8B Polyclonal Antibody品牌：solarbio | 貨號：K003646P

英文名稱Anti-CD8B Polyclonal Antibody
宿主Rabbit
別名CD8B1;LEU2;LY3;LYT3;P37
應用WB
稀釋比例WB 1:200-500.
交叉反應 Human Mouse Rat
蛋白分子量24kDa
Gene ID926
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CD8B
性狀液體
Public Immunogen RangeRecombinant protein of human CD8B
Subcellular LocationsCell membrane Secreted Single-pass type I membrane protein Single-pass type I membrane protein
Swiss ProtP10966
克隆類型 Polyclonal Antibody
背景資料The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

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