Anti-SMAD2PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
平臺授權一級代理，咨詢微信：jinshanbio
Anti-SMAD2 Polyclonal Antibody品牌：solarbio | 貨號：K005398P| 英文名稱 | Anti-SMAD2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | JV18;JV18-1;MADH2;MADR2;hMAD-2;hSMAD2 |
| 應用 | WB IHC IF |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 4087 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human SMAD2 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human SMAD2 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q15796 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. |
授權一級代理請認準金山科研平臺，產品價格和貨期請咨詢微信：jinshanbio ，詢價請加微信：jinshanbio
? Bio-Rad伯樂官網 |伯樂授權代理 |伯樂ddPCR| 伯樂Aminex| 伯樂層析填料色譜柱是專業的授權總代理區域代理經銷平臺。
? 如需詢價，請加客服QQ：1749072012 、客服微信：jinshanbio，或發送郵件到1749072012@qq.com
? 平臺為生命科學研究相關領域提供一站式耗材試劑儀器解決方案和采購服務，數據資源基于CC協議。
? 本文地址：http://www.yeybxjkgt.cn/thread-60782.htm
? 如需詢價，請加客服QQ：1749072012 、客服微信：jinshanbio，或發送郵件到1749072012@qq.com
? 平臺為生命科學研究相關領域提供一站式耗材試劑儀器解決方案和采購服務，數據資源基于CC協議。
? 本文地址：http://www.yeybxjkgt.cn/thread-60782.htm
特別聲明：以上內容(如有圖片亦包括在內)來源于授權廠家或網絡，如有侵權，請聯系客服刪除，本平臺不提供信息校正和存儲服務。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.
產品詢價需求提交
猜你喜歡：
掃碼添加客服微信，咨詢產品報價
QQ:1749072012
熱門標簽
相關推薦
最近更新：
為你推薦：