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Anti-NCALDPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-NCALD Polyclonal Antibody品牌：solarbio | 貨號：K005613P

英文名稱Anti-NCALD Polyclonal Antibody
宿主Rabbit
別名NCALD
應用WB IHC IF
稀釋比例WB 1:500-2000. IHC 1:50-200. IF 1:50-100.
交叉反應 Human Mouse Rat
蛋白分子量22kDa
Gene ID83988
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human NCALD
性狀液體
Public Immunogen RangeRecombinant protein of human NCALD
Subcellular LocationsCytosol Golgi apparatus
Swiss ProtP61601
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.

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