Anti-NDUFV1PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-NDUFV1 Polyclonal Antibody品牌：solarbio | 貨號：K005622P| 英文名稱 | Anti-NDUFV1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | CI-51K;CI51KD;UQOR1 |
| 應用 | WB IF |
| 稀釋比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 51kDa |
| Gene ID | 4723 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human NDUFV1 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human NDUFV1 |
| Subcellular Locations | Mitochondrion |
| Swiss Prot | P49821 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson’s disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
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