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Anti-CFDPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CFD Polyclonal Antibody品牌：solarbio | 貨號：K005667P

英文名稱Anti-CFD Polyclonal Antibody
宿主Rabbit
別名ADIPSIN;ADN;DF;PFD
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-100.
交叉反應 Human Mouse
蛋白分子量27kDa
Gene ID1675
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CFD
性狀液體
Public Immunogen RangeRecombinant protein of human CFD
Subcellular LocationsSecreted
Swiss ProtP00746
克隆類型 Polyclonal Antibody
背景資料This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.

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