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Anti-Phospho-PDGFRA-Y849PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-Phospho-PDGFRA-Y849 Polyclonal Antibody品牌：solarbio | 貨號：K006241P

英文名稱Anti-Phospho-PDGFRA-Y849 Polyclonal Antibody
宿主Rabbit
別名CD140A;PDGFR-2;PDGFR2
應用WB
稀釋比例WB 1:500-2000.
交叉反應 Human
蛋白分子量123kDa
Gene ID5156
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A phospho specific peptide corresponding to residues surrounding Y849 of human PDGFRA
性狀液體
Public Immunogen RangeA phospho specific peptide corresponding to residues surrounding Y849 of human PDGFRA
Subcellular LocationsCell membrane Single-pass type I membrane protein
Swiss ProtP16234
克隆類型 Polyclonal Antibody
背景資料This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

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