Anti-ICOSPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-ICOS Polyclonal Antibody品牌：solarbio | 貨號：K006766P| 英文名稱 | Anti-ICOS Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | AILIM;CD278;CVID1 |
| 應用 | IHC |
| 稀釋比例 | IHC 1:20-100. |
| 交叉反應 | Human |
| 蛋白分子量 | 23kDa |
| Gene ID | 29851 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human ICOS |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human ICOS |
| Subcellular Locations | Cell membrane Cytoplasm |
| Swiss Prot | Q9Y6W8 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. |
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