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Anti-EID3PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-EID3 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K007705P

英文名稱(chēng)Anti-EID3 Polyclonal Antibody
宿主Rabbit
別名NS4EB;NSE4B;NSMCE4B
應(yīng)用WB IHC
稀釋比例WB 1:200-1000. IHC 1:25-100.
交叉反應(yīng) Human Mouse
蛋白分子量38kDa
Gene ID493861
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human EID3
性狀液體
Public Immunogen RangeA synthetic peptide of human EID3
Subcellular LocationsCytoplasm
Swiss ProtQ8N140
克隆類(lèi)型 Polyclonal Antibody
背景資料EID3is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

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