Anti-ANTXR1PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-ANTXR1 Polyclonal Antibody品牌：solarbio | 貨號：K008074P| 英文名稱 | Anti-ANTXR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | ATR;TEM8 |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 84168 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human ANTXR1 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human ANTXR1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9H6X2 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. |
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