Anti-AGR2PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-AGR2 Polyclonal Antibody品牌：solarbio | 貨號：K004983P| 英文名稱 | Anti-AGR2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | AG-2;AG2;GOB-4;HAG-2;HEL-S-116;HPC8;PDIA17;XAG-2 |
| 應用 | WB |
| 稀釋比例 | WB 1:500-2000. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 20kDa |
| Gene ID | 10551 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human AGR2 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human AGR2 |
| Subcellular Locations | Endoplasmic reticulum Secreted |
| Swiss Prot | O95994 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. |
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