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Anti-PTPREPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-PTPRE Polyclonal Antibody品牌：solarbio | 貨號：K005089P

英文名稱Anti-PTPRE Polyclonal Antibody
宿主Rabbit
別名HPTPE;PTPE;R-PTP-EPSILON
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量81kDa
Gene ID5791
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human PTPRE
性狀液體
Public Immunogen RangeRecombinant protein of human PTPRE
Subcellular LocationsCell membrane Cytoplasm Cytoplasm Single-pass type I membrane protein
Swiss ProtP23469
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.

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