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Anti-ARCPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-ARC Polyclonal Antibody品牌：solarbio | 貨號：K008318P

英文名稱Anti-ARC Polyclonal Antibody
宿主Rabbit
別名Arg3.1
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量45kDa
Gene ID23237
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human ARC
性狀液體
Public Immunogen RangeRecombinant protein of human ARC
Subcellular LocationsCytoplasm
Swiss ProtQ7LC44
克隆類型 Polyclonal Antibody
背景資料Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.

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