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Anti-EID1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-EID1 Polyclonal Antibody品牌：solarbio | 貨號：K007024P

英文名稱Anti-EID1 Polyclonal Antibody
宿主Rabbit
別名CRI1;EID-1;RBP21;PTD014;C15orf3;PNAS-22;IRO45620
應用WB IHC
稀釋比例WB 1:200-1000. IHC 1:25-100.
交叉反應 Human Mouse
蛋白分子量21kDa
Gene ID23741
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human EID1
性狀液體
Public Immunogen RangeRecombinant protein of human EID1
Subcellular LocationsNucleus Cytoplasm
Swiss ProtQ9Y6B2
克隆類型 Polyclonal Antibody
背景資料E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.

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