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Anti-MANFPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-MANF Polyclonal Antibody品牌：solarbio | 貨號：K007651P

英文名稱Anti-MANF Polyclonal Antibody
宿主Rabbit
別名ARP;ARMET
應用IHC
稀釋比例IHC 1:100-300.
交叉反應 Human Mouse Rat
蛋白分子量21kDa
Gene ID7873
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human MANF
性狀液體
Public Immunogen RangeA synthetic peptide of human MANF
Subcellular LocationsCytoplasm
Swiss ProtP55145
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

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