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Anti-CAPNS1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-CAPNS1 Polyclonal Antibody品牌：solarbio | 貨號：K004596P

英文名稱Anti-CAPNS1 Polyclonal Antibody
宿主Rabbit
別名CALPAIN4;CANP;CANPS;CAPN4;CDPS;CSS1
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量28kDa
Gene ID826
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human CAPNS1
性狀液體
Public Immunogen RangeRecombinant protein of human CAPNS1
Subcellular LocationsCell membrane Cytoplasm
Swiss ProtP04632
克隆類型 Polyclonal Antibody
背景資料This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

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