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Anti-FMR1PolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-FMR1 Polyclonal Antibody品牌:solarbio | 貨號:K004105P

英文名稱Anti-FMR1 Polyclonal Antibody
宿主Rabbit
別名FMRP;FRAXA;POF;POF1
應用WB IHC IF
稀釋比例WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反應 Human Mouse Rat
蛋白分子量71kDa
Gene ID2332
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human FMR1
性狀液體
Public Immunogen RangeRecombinant protein of human FMR1
Subcellular LocationsCytoplasm Nucleus nucleolus
Swiss ProtQ06787
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

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