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Anti-GCDHPolyclonalAntibody-一抗-抗體-蛋白與免疫

2023-10-29

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Anti-GCDH Polyclonal Antibody品牌：solarbio | 貨號：K005992P

英文名稱Anti-GCDH Polyclonal Antibody
宿主Rabbit
別名ACAD5;GCD
應用WB
稀釋比例WB 1:200-2000.
交叉反應 Human Mouse Rat
蛋白分子量48kDa
Gene ID2639
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human GCDH
性狀液體
Public Immunogen RangeRecombinant protein of human GCDH
Subcellular LocationsMitochondrion matrix
Swiss ProtQ92947
克隆類型 Polyclonal Antibody
背景資料The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.

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