Anti-IDH3BPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-IDH3B Polyclonal Antibody品牌：solarbio | 貨號：K006914P| 英文名稱 | Anti-IDH3B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | RP46;H-IDHB |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 42kDa |
| Gene ID | 3420 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human IDH3B |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human IDH3B |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O43837 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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