Anti-PHOX2BPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-PHOX2B Polyclonal Antibody品牌：solarbio | 貨號：K006047P| 英文名稱 | Anti-PHOX2B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | NBLST2;NBPhox;PMX2B |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 32kDa |
| Gene ID | 8929 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human PHOX2B |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human PHOX2B |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q99453 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. |
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